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Systems Immunology & Immunotechnology
Our Team.
Principal Investigator
Yarive Wine, PhD.
Green Building, room 222
The Shmunis School of Biomedicine and Cancer Research
Faculty of Life Sciences
Tel Aviv University
Ramat Aviv
Israel, 6997801
Tel: +972 3 6408723
Email: yarivwine@tauex.tau.ac.il
Laboratory Manager
Yael Dror, M.Sc
Green building, room 224
The Shmunis School of Biomedicine and Cancer Research
Faculty of Life Sciences
Tel-Aviv University
Ramat-Aviv
Israel, 6997801
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Tel: +972 3 640 7518 Fax: +972 3 640 5147
Email: Dror11@tauex.tau.ac.il
PhD. Students
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PhD. Student (co-advisor Prof. Noga Kronfeld-Schor)
Hagar Naim
Hagar joined the group in May 2021 as a PhD student after completing her M.Sc. in Ecology and Environmental Studies at the Faculty of Life Sciences, Tel Aviv University.
Her PhD research focuses on investigating the effects of light pollution on the immune system, with an emphasis on the intricate interplay between the biological clock and both adaptive and innate immune responses.
To explore the role of the biological clock in regulating immune function, Hagar employs a unique animal model (Acomys spp.) that includes both nocturnal and diurnal species.
PhD. Student
Aya Kigel
Aya joined our group in October 2017 after completing her BSc. at the Robert H. Smith faculty of agriculture, food and environment, Hebrew University of Jerusalem.
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During her PhD, Aya focus on the molecular landscape of B cell immunity at the maternal-infant interface which involves the study of maternal immunization.
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In her MSc. project Aya focused on developing computational and experimental frameworks for proteomic analysis of serum antibodies.
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PhD. Student
Ligal Aizik
Ligal joined our group in May 2019 after completing her B.Sc in Biotechnology at the faculty of Life Sciences, Tel Aviv University.
In her PhD project Ligal is working on characterizing the phenotype of tumor infiltrating B lymphocytes, tumor-associated B cells and their distinct antibody repertoire.
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During her BSc she gained experience as research assistant in our lab, working on production, purification and validation of Tetanus Toxoid C fragment (rTTC), and purification of rTTC and TT-specific antibodies from pregnant women.
PhD. Student
David Taussig
David joined our group in May 2020 after completing his BSc. in biomedical engineering at UAS Vienna, Austria.
He completed his M.Sc in biotechnology and is currently developing a platform leveraging NGS and phage display towards the discovery of antimicrobial antibodies for his PhD.
PhD. Student
Talya Bar-Am
Talya joined our group in October-2021 after completing her B.Sc in Biology at the faculty of Life Sciences, Tel Aviv University.
She completed her MSc. In biotechnology in our Lab. Talya's project is Harnessing Human Milk B Cells for Antibody-Based Strategies to Combat Bacterial Pathogens
PhD. Student
Yael Shenkerman
Yael joined our group in March 2024 as a PhD student. She previously earned her M.Sc in Life Sciences from Ben-Gurion University and holds an MBA in Technology Management, Innovation & Entrepreneurship from Tel Aviv University.
Yael’s research focuses on characterizing memory B cell (MBC) subphenotypes generated by vaccination, aiming to understand their distinctions from infection-induced MBCs.
Her project investigates the functional roles of MBC subphenotypes in immune protection and response durability, with the goal of identifying biomarkers predictive of vaccine efficacy. This work could ultimately advance vaccine design by illuminating mechanisms that support long-lasting immune memory and protection.
PhD. Student
Gaya Roga
Gaya joined our group in October 2022 after completing her B.Sc in Biology in Life Sciences at Tel-Aviv University.
Her M.Sc research focused focused on developing computational and experimental frameworks for proteomic analysis of serum antibodies.​
PhD. Student
Meital Mazin
Meital joined our group in October 2022 after completing her B.Sc in the Interdisciplinary Program in Medical and Life Sciences at Tel-Aviv University.
Her M.Sc research focused on identifying distinct tumor-infiltrating B cell (TIL-B) populations in triple-negative breast cancer (TNBC) and investigating IgA secretion within the mucosal TNBC microenvironment. This work involved an extensive computational analysis of single-cell sequencing data.
For her Ph.D., she will continue characterizing TIL-Bs, expanding her research to pediatric acute lymphoblastic leukemia.
M.Sc Students
M.Sc Student
Shira Melki
Shira joined our group in October 2023 after completing her B.Sc in Biology at the Faculty of Life Sciences, Tel Aviv University.
Her research focuses on isolating and characterizing tumor-specific antibodies from the tumor microenvironment, with particular emphasis on patients with non-small cell lung cancer (NSCLC).
This project aims to identify antibodies that could play a role in targeted cancer therapies by harnessing the body’s natural immune response.
M.Sc Student
Noam Ofri
Noam joined our group in October 2023 after completing her B.Sc in Biology at the Faculty of Life Sciences, Tel Aviv University.
Her research focuses on antibacterial antibodies engineering.
M.Sc Student
Maya Chen
Maya joined our group in October 2024 after completing her B.Sc in Biotechnology and Biology at the faculty of Life Sciences, Tel Aviv University.
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M.Sc Student
Neta Even-Tov
Neta joined our group in October 2024 after completing her B.Sc in Biotechnology and Biology at the faculty of Life Sciences, Tel Aviv University.
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Alumni
M.Sc Student
Bar Avidov
Bar joined our group in October 2022 after completing his B.Sc in Biology at the faculty of Life Sciences, Tel Aviv University.
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He completed his M.sc. in Computational Biology. His research project focused on studying paratope-epitope interactions in antibodies.
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M.Sc Student
Camilla Terracina
Camilla joined our group in October-2021 after completing B.Sc in biology at the Faculty of Life Science, Sapienza University of Rome.
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In her M.Sc Camilla worked on the dynamics of the vaccine-specific antibody and mother-baby interface.
PhD. Student
Shai Rosenstein
Shai joined our group in October 2015 after completing her B.Sc at the Faculty of Life Sciences, Tel Aviv University.
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During her B.Sc studies she worked as a research assistant in the Department of Zoology and in the Department of Molecular Microbiology and Biotechnology.
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In her MSc. project Shai focused on the characterization of the antibodies elicited following infusion of anti-TNFa agent (Infliximab) to IBD patients. Specifically, Shai will look for associations between neutralizing anti drug antibodies and various cytokines (e.g. BAFF).
M.Sc Student
Limor Levy
Limor joined our group in April 2016 after completing her masters thesis at the Department of Molecular Microbiology and Biotechnology, Tel Aviv University.
During her PhD, Limor focused on the impact of pregnancy on the nature of the immune response following maternal immunization.
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In her MSc studies, she developed an ex-vivo system for high-throughput analysis of molecular chaperon as therapeutic strategy for the Von Hipple–Lindau syndrome.
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Alongside her PhD research, Limor tutored future scientists from the ‘Tel Aviv University for youth’ that promotes young scientists to discover and research in the academy during mid and high school.
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M.Sc Student
Tsuf Eyran
​Tsuf joined the Wine lab in October 2019 after completing his B.Sc in Life Sciences in the Faculty of Life Sciences at Ben-Gurion University.
Tsuf focused his study and research on the longitudinal kinetics of the serological response in COVID-19 recovered patients over the period of 14 months with a comparison to the differences and effects in longitudinal kinetics between recovered patients, naïve BNT162b2 vaccinees and recovered patients post vaccination.
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PhD. Student (co-advisor Prof. Itay Benhar)
Anna Vaisman Mentesh
Anna joined our group in October 2014 after completing her M.Sc thesis at the Department of Molecular Microbiology and Biotechnology.
In her PhD. project Anna worked on analyzing the drug-antibody repertoire in inflammatory bowel disease patients treated with Infliximab.
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During her M.Sc she worked on developing an animal model for in-vivo restoration of p53 cancer associated mutations and the development of a novel method of examining p53 DNA binding.
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Research Associate
Yaron Hillman, PhD.
Yaron completed his PhD. in Tel Aviv University, at the Department of Cell and Developmental Biology, Sackler faculty of Medicine, under the supervision of Prof. Zvi Fishelson.
Yaron worked on a novel therapeutic monoclonal antibody to combat multidrug-resistant (MDR) pathogenic bacteria.
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In his PhD. he studied and characterized microRNAs that modulated the sensitivity of cancer cells to complement-dependent cytotoxicity.
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M.Sc Student
Dan Lustiger
Dan joined our group in October 2017 after completing his BSc. in Marine Biotechnology at the Ruppin Academic Center.
During his BSc. Dan participated in a research project under the supervision of Dr. Nir Nesher & Dr. Tal Shomrat which focused on characterization of structure and anti-bacterial activity of Octopus vulgaris skin mucus. In addition, his M.Sc involved the study of anti-bacterial immunotherapy.
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